WEDNESDAY, March 4, 2020 — Nearly 14 percent of children aged 3 to 17 years had ever been diagnosed with attention-deficit/hyperactivity disorder (ADHD) or a learning disability in 2016 to 2018, according to a March data brief published by the U.S….
Fragile X syndrome (FXS) was first clinically described in 1943 by Martin-Bell and in 1969 Lubs found a fragility at the terminal end of the X chromosome. In 1991, three different research groups independently cloned the mutation for the FMR1 gene (Fragile X mental retardation type 1) which has a CGG triplet expansion. The FMR1 gene codes for the FMR protein which is a major regulator of synaptic plasticity and is expressed in the brain and spermatogonia mainly but many other tissues during fetal and early neonatal development. The number of triplets and methylation correlates with clinical expression (increased…
CONTEXT: In the absence of baseline testing, normative data may be used to interpret postconcussion scores on the clinical reaction-time test (RTclin). However, to provide normative data, we must understand the performance factors associated with baseline testing.
OBJECTIVE: To explore performance factors associated with baseline RTclin from among candidate variables representing demographics, medical and concussion history, self-reported symptoms, sleep, and sport-related features.
DESIGN: Cross-sectional study.
SETTING: Clinical setting (eg, athletic training room).
PATIENTS OR OTHER…
CONCLUSION: It should be routine to screen for cognitive and behavioral difficulties for all patients with DS. There is a need for more robust studies regarding intellectual and behavioral disorders in patients with DS. These should be large population-based or multinational studies that employ standardized instruments.
PMID: 32334365 [PubMed – as supplied by publisher]
This study examined mathematics achievement in school-aged children with autism spectrum disorder (ASD), symptoms of attention-deficit/hyperactivity disorder (ADHD), or typical development (TD) over a 30-month period and the associations between cognitive and reading abilities with mathematics achievement in children with ASD. Seventy-seven children with ASD without intellectual disability (ASD-WoID), 39 children with ADHD, and 43 children with TD participated in this study. The results revealed that the ASD-WoID and ADHD samples displayed significant and comparable delays in problem solving and calculation abilities. Lowe…
Authors: Andrade C
Many observational studies have found an association between antidepressant drug prescription during pregnancy and neurodevelopmental disorders such as autism spectrum disorder, attention-deficit/hyperactivity disorder, and intellectual disability. The results of such studies cannot be considered conclusive because of the possible presence of inadequately measured, unmeasured, and unknown confounds. In this context, maternal anemia before or at but not after 30 weeks of gestation was recently associated with an increased risk of all 3 of these neurodevelopmental disorders. Additionally, …
Conclusions: Further research is needed to examine the role of sex, race, ADHD, and concussion history on concussion outcomes.
PMID: 32200661 [PubMed – as supplied by publisher]
Publication date: May 2020Source: Research in Developmental Disabilities, Volume 100Author(s): Matthew Carl Zajic, Emily Jane Solari, Nancy Susan McIntyre, Lindsay Lerro, Peter Clive Mundy
BACKGROUND: Over recent decades, the number of students diagnosed with learning disabilities and/or attention deficit hyperactivity disorders has substantially increased. These students face various challenges and experience stress when receiving higher ed…
Authors: Léger M, Piat N, Jean FA, Galera C, Bouvard MP, Amestoy A
OBJECTIVES: Different studies centered on social relationship issues among ADHD children struggled to provide a unicist explanation between primary social cognition process alteration on the one hand and a mere symptomatic outcome of the disorder triad on the other. Some authors support the idea of a potential “social phenotype” shared at a different intensity by Attention Deficit/Hyperactivity Disorder (ADHD) and Autism Spectrum Disorder (ASD). The point of the study is to characterize this possible social disability in a …
Publication date: May 2020Source: Research in Developmental Disabilities, Volume 100Author(s): Ranit Gabriely, Ricardo Tarrasch, Maria Velicki, Zehava Ovadia-Blechman