Is rapid exome sequencing standard of care in the NICU and PICU?

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In this volume of The Journal, Freed report results of a 3-year trial of the clinical utility of rapid exome sequencing (rES) in critically ill children in the neonatal, pediatric and cardiac intensive care units (ICU) of a tertiary children’s hospital. The authors conclude that rES should be considered standard of care for some such children. For readers who are not – yet – aficionados of rapid genomic medicine, let me provide some context for this provocative statement.

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