Leonardo da Vinci May Have Had ADHD


FRIDAY, May 24, 2019 — Leonardo da Vinci’s legendary struggles to complete projects suggest he may have had attention-deficit hyperactivity disorder (ADHD), a British researcher says.
That’s the latest in a series of attempts to understand the…

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PURPOSE: Epidemiologic findings are inconsistent regarding the association between attention-deficit/hyperactivity disorder (ADHD) medication exposure and suicide attempt in individuals with ADHD.

METHODS: A systematic literature search of PubMed, Emba…

Source: SafetyLitCategory: International Medicine & Public Health Tags: Research Methods, Surveillance and Codes, Models Source Type: news

This study sheds light on the initiation, maintenance, and identification of polypharmacy psychotropic regimens and highlights psychosocial treatment as an intervention that increases best practice care for at-risk patients.
PMID: 32878541 [PubMed – as supplied by publisher]

Source: Psychiatric ServicesCategory: Psychiatry Tags: Psychiatr Serv Source Type: research

AbstractMany interventions targeting executive function (EF) development in the preschool period, where malleability might be particularly high, have been created and evaluated. We conducted a meta-analysis of randomized controlled trials (RCTs) on the effects of these interventions on (a) EFs in preschool children from the general population as well as preschool children with (symptoms of) attention-deficit hyperactivity disorder (ADHD) and oppositional defiant disorder (ODD), and (b) ADHD and ODD symptoms in preschool children with ADHD/ODD (symptoms). Literature search yielded 35 RCTs. Risk of bias of the individual stu…

FRIDAY, Sept. 4, 2020 — Having attention-deficit/hyperactivity disorder (ADHD) symptoms that persist into adulthood is associated with a higher risk for being involved in a motor vehicle crash (MVC), according to a study published online Aug. 22 in…


Source: Nutritional NeuroscienceCategory: Nutrition Authors: Source Type: research

This study is based on the Finnish Prenatal Study of ADHD with a nested case–control design. All the singleton children born in Finland between January 1998 and December 1999 and diagnosed with ADHD were included in the study. A total of 1026 cases were matched with an equal numb er of controls on sex, date of birth and place of birth. Maternal Vitamin B12 levels were assessed using a chemiluminescence microparticle immunoassay and archived from maternal serum banks, collected during the first and early second trimester of pregnancy. Lower maternal Vitamin B12 levels when an alyzed as a continuous variable was not as…

Fragile X syndrome (FXS) is the most common identifiable cause of inherited intellectual disability and autism spectrum conditions, and is associated with a range of physical, cognitive and behavioural characteristics. Alongside intellectual disability, heightened rates of autism spectrum disorder, anxiety disorders, attention-deficit-hyperactivity disorder, self-injury and aggression are reported. Timely identification of FXS as well as assessments of common co-morbid psychological conditions and underlying health problems are essential to ensure individuals with FXS receive appropriate support.

Source: Paediatrics and Child HealthCategory: Pediatrics Authors: Tags: Personal practice Source Type: research

DiscussionThis umbrella review of associations between maternal prenatal use of analgesic drugs and children ’s neurodevelopmental disorders could allow for firmer conclusions to be drawn through the synthesis of all relevant published research. The synthesis of findings using high-quality evidence could provide more accurate healthcare information on the long-term effects of analgesic drugs on neurodeve lopment, to better guide future clinical decisions during pregnancy. This review will also allow gaps and methodological differences in the literature to be identified, informing recommendations for future research.S…

Source: Systematic ReviewsCategory: International Medicine & Public Health Source Type: research

The objective of our study was to evaluate the frequency of treatable inborn errors of metabolism (IEM) in a clinical sample of Mexican children and adolescents with neurodevelopmental disorders (NDD). Amino acids and acylcarnitines in blood samples of 51 unrelated children and adolescents were analyzed by tandem mass spectrometry to detect treatable IEM of small molecules. One patient with isovaleric acidemia and autism spectrum disorder (ASD) and another with beta-ketothiolase deficiency and ASD/intellectual disability/attention-deficit/hyperactivity disorder (ADHD) were diagnosed, indicating an IEM frequency of 3.9% (1:…

Source: Journal of Autism and Developmental DisordersCategory: Psychiatry Authors: Tags: J Autism Dev Disord Source Type: research

Antidepressants are prescribed for the treatment of a number of psychiatric disorders in children and adolescents, however there is still controversy about whether they should be used in this population. This meta-review aimed to assess the effects of antidepressants for the acute treatment of attention-deficit/hyperactivity disorder (ADHD), anxiety disorders (ADs), autistic spectrum disorder (ASD), enuresis, major depressive disorder (MDD), obsessive-compulsive disorder (OCD), and posttraumatic stress disorder (PTSD) in children and adolescents. Efficacy was measured as response to treatment (either as mean overall change…

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