Persistence of ADHD into adulthood is an important predictor of car crash risk

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(Elsevier) A new study reports that the risk of being involved in car crashes increases for those diagnosed with attention-deficit/hyperactivity disorder (ADHD). The study in the Journal of the American Academy of Child and Adolescent Psychiatry (JAACAP), published by Elsevier, looked specifically at the rate of car crashes by adulthood, which was 1.45 times higher in those with a childhood history of ADHD compared to adults with no ADHD.

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Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disorder among children resulting in disturbances in their daily functioning. Virtual reality (VR) and machine learning technologies, such as deep learning (DL) application, are promising diagnostic tools for ADHD in the near future because VR provides stimuli to replace real stimuli and recreate experiences with high realism. It also creates a playful virtual environment and reduces stress in children. The DL model is a subset of machine learning that can transform input and output data into diagnostic values using convolutional neural network …

Translational Psychiatry, Published online: 17 August 2020; doi:10.1038/s41398-020-00971-7Polygenic risk score analysis revealed shared genetic background in attention deficit hyperactivity disorder and narcolepsy

Source: Translational PsychiatryCategory: Psychiatry Authors: Source Type: research

ConclusionThe ever-increasing prescription of ADHD medicines stopped some years ago for children. ADHS and its pharmacological management are increasingly observed among older adolescents and adults, with a different pattern of drug persistence compared with children.

Conclusions: Although both teachers and parents recognized ADHD symptoms, they were generally more recognized by teachers than by parents.
PMID: 32794170 [PubMed – in process]

Publication date: Available online 15 August 2020Source: Annals of Medicine and SurgeryAuthor(s): Laila T. Ababneh, Mahmoud Bashtawi, Bayan F. Ababneh, Ikhlas H. Mahmoud, Mohammad Rashdan, Mohammad Zahran

ConclusionsOur DNAm data provide insights into the regulatory changes associated with genetic variation, highlighting their potential utility both in directing GWAS and in elucidating the pathophysiology of neurodevelopmental disorders.

CONCLUSIONS: Our findings suggest that NLR and PLR may be inflammation biomarkers in children and adolescents with ADHD. Moreover, the significance of NLR is not influenced by medication use, age and sex. Prospective studies that address alterations in NLR and PLR and other pro-inflammatory cytokines following ADHD treatment may provide additional information about the inflammatory mechanisms in ADHD. Key points The mean NLR and PLR were significantly higher in patients than in controls. The significance of NLR is not influenced by medication use, age and sex. No associations were found between NLR and PLR and ADHD symptom…

The association between Attention Deficit Hyperactivity Disorder (ADHD) and suicidal ideation has been the focus of recent research interest among youths and young adults. However, the role perceived stress plays in this association is unclear. We investig…

Source: SafetyLitCategory: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Publication date: November 2020Source: Neuroscience &Biobehavioral Reviews, Volume 118Author(s): Maja Dobrosavljevic, Carmen Solares, Samuele Cortese, Henrik Andershed, Henrik Larsson

CONCLUSION: These findings provide additional evidence for dysregulation of the blood-brain barrier, especially abnormalities in claudin-5 function, which may be involved in the aetiology of ADHD. Key points ADHD is one of the most common neurodevelopmental disorders of childhood. Although ADHD is quite common, its aetiology has yet to be fully explained. In recent years, studies on the relationship between intestinal and blood-brain brain barrier permeability and psychiatric disorders have increased. In our study, serum claudin-5 levels were higher in the ADHD group compared to the control group, while serum zonulin level…

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