OBJECTIVE: Attention deficit hyperactivity disorder (ADHD) is one of the most common problems in adolescents. Risky behaviors in patients with ADHD are due to impaired impulse control resulting from problems with inhibition of proponent responses, controll…
Condition: Attention Deficit Hyperactivity Disorder Intervention: Drug: Centanafadine Sponsor: Otsuka Pharmaceutical Development&Commercialization, Inc. Not yet recruiting
AbstractPurpose of ReviewCannabis exposure during critical windows of development may have intergenerational physiological consequences disrupting epigenetic programming and marks. This review examines the literature relating to pre-gestational and prenatal cannabinoid exposure and its effect on genes and molecular pathways related to the development of psychiatric disease.Recent FindingsDevelopmental cannabis exposure alters epigenetic processes with functional gene consequences. These include potentially heritable alterations in genes and molecular pathways critical for brain development and associated with autism spectr…
CONCLUSIONS: A lower macular thickness was observed in patients with ADHD than in controls. In addition, patients with ADHD without treatment had a lower thickness of the fovea and RNFL than those patients on treatment.
PMID: 32423628 [PubMed – as supplied by publisher]
Publication date: July 2020Source: Journal of Adolescence, Volume 82Author(s): O. Dan
The Journal of Alternative and Complementary Medicine, Ahead of Print.
Journal of Child and Adolescent Psychopharmacology, Ahead of Print.
AbstractAttention-deficit/hyperactivity disorder (ADHD) is a prevalent and serious disorder among children. Video games have shown potential for aiding in child healthcare. Video games could contribute to the assessment and management of ADHD, but there are no previous reviews on this topic. Here, we systematically review the evidence about video game-based assessment tools and interventions for children diagnosed with ADHD. This review followed the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines. The review protocol was registered in PROSPERO database. We searched four databases &mda…
CONCLUSIONS: These results represent some of the most compelling evidence to date of the enduring power of early, time-limited childhood adversity to impair long-term neuropsychological functioning across the lifespan – effects that are linked specifically to deprivation-related adult ADHD symptoms.
PMID: 32419675 [PubMed – as supplied by publisher]