Study finds brain defects in people with a genetic risk for schizophrenia


FINDINGSAn international study led by researchers from the Jane and Terry Semel Institute for Neuroscience and Human Behavior at UCLA has found that people who are born with a genetic disease that greatly increases the risk of developing schizophrenia  have distinctive defects and deficiencies in the white matter of their brains. Researchers compared the brains of people with the genetic disorder, 22q11.2 deletion syndrome, to the brains of healthy people and to the brains of people with the disease who do not have schizophrenia.The brain ’s white matter connects different regions of the brain and allows neurons to communicate with each other. The paper also reports that abnormalities in white matter could help explain why people with 22q11.2 deletion syndrome have difficulties orga…

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