The influence of depression and school life on the quality of life of Korean child and adolescent patients with attention-deficit/hyperactivity disorder:a comparison of the perspectives of the patients and their caregivers

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This study aimed to compare the quality of life reported by patients with attention-deficit/hyperactivity disorder (ADHD) to the patients’ quality of life as reported by their caregivers. In addition, it aimed to examine how emotional pr…

Source: SafetyLitCategory: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

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by Beate Leppert, Louise A. C. Millard, Lucy Riglin, George Davey Smith, Anita Thapar, Kate Tilling, Esther Walton, Evie Stergiakouli

Psychiatric disorders are highly heritable and associated with a wide variety of social adversity and physical health problems. Using genetic liability (rather than phenotypic measures of disease) as a proxy for psychiatric disease risk can be a useful alternative for research questions that would traditionally require large cohort studies with long-term follow up. Here we conducted a hypothesis-free phenome-wide association study in about 300,000 participants from the UK Biobank to examine…

Source: PLoS GeneticsCategory: Genetics & Stem Cells Authors: Source Type: research

AbstractPurpose of ReviewThe main purpose of this review is to understand how attention deficit hyperactivity disorder (ADHD) affects geriatrics (elderly population).Recent FindingsADHD is a common neuropsychiatric condition, which is not well studied in geriatrics. Current literature does not have too much information on effects of ADHD in geriatrics. ADHD in elderly population is accompanied by various comorbidities such as anxiety and depression.SummaryThis review will provide an overview of existing literature on prevalence of ADHD in elderly population along with the comorbidities and available treatment options for the same.

CONCLUSIONS: ADHD and SCT symptoms and concerns in college students may be related to poor sleep, which can lead to misdiagnosis for individuals presenting with ADHD-like complaints for the first time in college. Sleep difficulties may be modifiable with empirically supported sleep interventions; thus, in assessment for either of these presentations, a careful sleep history should be taken.
PMID: 32380521 [PubMed – as supplied by publisher]

This study examined the complex relationships between QoL, school bullying, suicide, and ADHD symptoms. A total of 203 adolescents with ADHD aged between 12 and 18 years were recruited. School bullying and QoL were examined using the Chinese version of the School Bullying Experience Questionnaire and the Taiwanese Quality of Life Questionnaire for Adolescents. Network model analysis was conducted to graphically present their relationships. We identified triangular correlations between school bullying, QoL, and suicidality, indicating possible pathways from school bullying to suicidality, and the originating or mediating ro…

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Abstract
BACKGROUND: Severe malocclusions appear in up to 20 per cent of the population. Many neuropsychiatric diseases are likely to have a neurodevelopmental, partially genetic background with their origins as early as fetal life. However, the possible relationship between neurodevelopmental disorders and severe malocclusions is unclear. The aim of this study was in a population-based setting (270 000 inhabitants) to investigate whether patients with severe malocclusions have more mental and behavioural disorders and growth or speech problems than controls without severe malocclusion.
MATERIAL AND M…

Source: European Journal of OrthodonticsCategory: Dentistry Authors: Tags: Eur J Orthod Source Type: research

Conclusions
Available data on homeopathy in psychiatric disorders are insufficient to support their use in clinical practice.

Children with reading and/or spelling disorders have increased rates of behavioral and emotional problems and combinations of these. Some studies also find increased rates of attention-deficit/hyperactivity disorder (ADHD), conduct disorder, anxiety disorder, and depression. However, the comorbidities of, e.g., arithmetic disorders with ADHD, anxiety disorder, and depression have been addressed only rarely. The current study explored the probability of children with specific learning disorders (SLD) in reading, spelling, and/or arithmetic to also have anxiety disorder, depression, ADHD, and/or conduct disorder. The sample …

Discussion
Fragile X syndrome (FXS) was first clinically described in 1943 by Martin-Bell and in 1969 Lubs found a fragility at the terminal end of the X chromosome. In 1991, three different research groups independently cloned the mutation for the FMR1 gene (Fragile X mental retardation type 1) which has a CGG triplet expansion. The FMR1 gene codes for the FMR protein which is a major regulator of synaptic plasticity and is expressed in the brain and spermatogonia mainly but many other tissues during fetal and early neonatal development. The number of triplets and methylation correlates with clinical expression (increased…

Source: PediatricEducation.orgCategory: Pediatrics Authors: Tags: Uncategorized Source Type: news

This article reviews the role of the main components of the ECS as biomarkers in certain psychiatric disorders. Studies carried out in rodents evaluating the effects of pharmacological and genetic manipulation of cannabinoid receptors or endocannabinoids (eCBs) degrading enzymes were included. Likewise, the ECS-related alterations occurring at the molecular level in animal models reproducing some behavioral and/or neuropathological aspects of psychiatric disorders were reviewed. Furthermore, clinical studies evaluating gene or protein alterations in post-mortem brain tissue or in vivo blood, plasma, and cerebrospinal fluid…

A 32-year-old child and adolescent psychiatry resident with a history of presenting an abstract at a local psychiatric conference during residency and fourth authorship on an immunotherapy paper from a summer internship during medical school presents with a new-onset desire to write a case report. She has just come off her consultation liaison rotation, during which she consulted on a 12-year-old boy with attention-deficit/hyperactivity disorder, oppositional defiant disorder, disruptive mood dysregulation disorder, and low depressive state hospitalized for pseudoseizures, a new-onset inability to walk, and aggressive outb…

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